The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results

Schotten, Ulrich; Hatem, Stephane; Ravens, Ursula; Jaïs, Pierre; Müller, Frank-Ulrich; Goette, Andres; Rohr, Stephan; Antoons, Gudrun; Pieske, Burkert; Scherr, Daniel; Oto, Ali; Casadei, Barbara; Verheule, Sander; Cartlidge, David; Steinmeyer, Klaus; Götsche, Thorsten; Dobrev, Dobromir; Kockskämper, Jens; Lendeckel, Uwe; Fabritz, Larissa; ... (2015). The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results. Europace, 17(10), pp. 1457-1466. Oxford University Press 10.1093/europace/euv252

[img] Text
Schotten2015Europace_1.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (830kB) | Request a copy
[img] Slideshow (Figures)
Fgures EUTRAF.pptx - Supplemental Material
Available under License Publisher holds Copyright.

Download (4MB)
[img]
Preview
Text
EUTRAF%20Review%20article%20150205%20final-1.pdf - Accepted Version
Available under License Publisher holds Copyright.

Download (181kB) | Preview
[img]
Preview
Text
euv252.pdf - Other
Available under License Publisher holds Copyright.

Download (827kB) | Preview

Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population. As an age-related arrhythmia AF is becoming a huge socio-economic burden for European healthcare systems. Despite significant progress in our understanding of the pathophysiology of AF, therapeutic strategies for AF have not changed substantially and the major challenges in the management of AF are still unmet. This lack of progress may be related to the multifactorial pathogenesis of atrial remodelling and AF that hampers the identification of causative pathophysiological alterations in individual patients. Also, again new mechanisms have been identified and the relative contribution of these mechanisms still has to be established. In November 2010, the European Union launched the large collaborative project EUTRAF (European Network of Translational Research in Atrial Fibrillation) to address these challenges. The main aims of EUTRAF are to study the main mechanisms of initiation and perpetuation of AF, to identify the molecular alterations underlying atrial remodelling, to develop markers allowing to monitor this processes, and suggest strategies to treat AF based on insights in newly defined disease mechanisms. This article reports on the objectives, the structure, and initial results of this network.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Physiology

UniBE Contributor:

Rohr, Stephan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1099-5129

Publisher:

Oxford University Press

Language:

English

Submitter:

Stefan von Känel-Zimmermann

Date Deposited:

13 Jan 2016 17:00

Last Modified:

01 Oct 2018 02:30

Publisher DOI:

10.1093/europace/euv252

BORIS DOI:

10.7892/boris.74583

URI:

https://boris.unibe.ch/id/eprint/74583

Actions (login required)

Edit item Edit item
Provide Feedback