Isolation of an active gene and of two pseudogenes for mouse U7 small nuclear RNA

Gruber, Andreas; Soldati, D; Burri, M; Schümperli, Daniel (1991). Isolation of an active gene and of two pseudogenes for mouse U7 small nuclear RNA. Biochimica et biophysica acta (BBA) - gene structure and expression, 1088(1), pp. 151-154. Elsevier 10.1016/0167-4781(91)90167-K

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Three U7 RNA-related sequences were isolated from mouse genomic DNA libraries. Only one of the sequences completely matches the published mouse U7 RNA sequence, whereas the other two apparently represent pseudogenes. The matching sequence represents a functional gene, as it is expressed after microinjection into Xenopus laevis oocytes. Sequence variations of the conserved cis-acting 5' and 3' elements of U RNA genes may partly explain the low abundance of U7 RNA.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Cell Biology

UniBE Contributor:

Gruber, Andreas and Schümperli, Daniel

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

0167-4781

Publisher:

Elsevier

Language:

English

Submitter:

Andreas Gruber

Date Deposited:

28 Jan 2016 15:32

Last Modified:

29 May 2017 18:17

Publisher DOI:

10.1016/0167-4781(91)90167-K

PubMed ID:

1989694

URI:

https://boris.unibe.ch/id/eprint/74827

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