Expanding Indications of Transcatheter Heart Valve Interventions.

Praz, Fabien; Windecker, Stephan; Huber, Christoph; Carrel, Thierry; Wenaweser, Peter Martin (2015). Expanding Indications of Transcatheter Heart Valve Interventions. JACC. Cardiovascular Interventions, 8(14), pp. 1777-1796. Elsevier 10.1016/j.jcin.2015.08.015

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Transcatheter aortic valve replacement (TAVR) has been established as a less invasive alternative to open-heart surgery in inoperable or high-risk patients presenting with symptomatic severe aortic valve stenosis. The feasibility and efficacy of valve-in-valve implantation in degenerated surgical aortic bioprostheses have also been described and can currently be considered a valuable treatment option in patients deemed unsuitable for repeat cardiac surgery. However, the clinical use of TAVR devices is not limited to the treatment of the tricuspid stenotic aortic valve. Several additional indications including treatment of the bicuspid stenotic aortic valve, aortic regurgitation, and valve-in-valve or valve-in-ring implantation in the mitral or tricuspid position as well as treatment of pure mitral, tricuspid, or pulmonary regurgitation have been described. The purpose of the present review is to summarize the available evidence concerning the emerging off-label use of TAVR devices in current clinical practice. Case examples have been selected to highlight the main procedural steps of each particular intervention.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery

UniBE Contributor:

Praz, Fabien; Windecker, Stephan; Huber, Christoph; Carrel, Thierry and Wenaweser, Peter Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1876-7605

Publisher:

Elsevier

Language:

English

Submitter:

Daniela Huber

Date Deposited:

04 Feb 2016 16:18

Last Modified:

11 Nov 2016 09:26

Publisher DOI:

10.1016/j.jcin.2015.08.015

PubMed ID:

26718509

BORIS DOI:

10.7892/boris.75074

URI:

https://boris.unibe.ch/id/eprint/75074

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