Open radical cystectomy: still the gold standard for muscle invasive bladder cancer

Kiss, Bernhard; Burkhard, Fiona C.; Thalmann, George (2016). Open radical cystectomy: still the gold standard for muscle invasive bladder cancer. World journal of urology, 34(1), pp. 33-39. Springer 10.1007/s00345-015-1729-7

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INTRODUCTION Muscle invasive bladder cancer is an unforgiving disease, and if untreated, it leads to death within 2 years of the diagnosis in >85 % of the patients. Long-term oncologic efficacy remains the ultimate standard that all procedures have to be measured by. In the past decades, open radical cystectomy (RC), extended pelvic lymph node dissection (PLND), and urinary diversion have been established as the gold standard. In the last few years, however, growing attention has been set on robotic-assisted radical cystectomy (RARC). RESULTS Even in the very long term, open RC has good oncological results and if an ileal neobladder is performed excellent functional results. Follow-up of patients after open RC exceeds more than a decade which is unsurpassed by any other technique. Its outcomes have been proven to be durable and cost-effective. Least perioperative complications as well as best oncological and functional results can be achieved if open RC and urinary diversion were performed in a high-volume hospital by high-volume surgeons and an experienced team. CONCLUSIONS Despite upcoming new technologies such as RARC, open RC following extended (PLND) remains the gold standard treatment for high-grade muscle invasive bladder cancer.

Item Type:

Journal Article (Review Article)


04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology

UniBE Contributor:

Kiss, Bernhard; Burkhard, Fiona C. and Thalmann, George


600 Technology > 610 Medicine & health








Katharina Morgenegg

Date Deposited:

08 Feb 2016 14:08

Last Modified:

30 Sep 2017 08:59

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Muscle invasive bladder cancer, Open radical cystectomy




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