Clinical acid-base pathophysiology: disorders of plasma anion gap.

Moe, Orson W; Fuster, Daniel Guido (2003). Clinical acid-base pathophysiology: disorders of plasma anion gap. Best practice & research - clinical endocrinology & metabolism, 17(4), pp. 559-574. Bailliere Tindall

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The plasma anion gap is a frequently used parameter in the clinical diagnosis of a variety of conditions. The commonest application of the anion gap is to classify cases of metabolic acidosis into those that do and those that do not leave unmeasured anions in the plasma. While this algorithm is useful in streamlining the diagnostic process, it should not be used solely in this fashion. The anion gap measures the difference between the unmeasured anions and unmeasured cations and thus conveys much more information to the clinician than just quantifying anions of strong acids. In this chapter, the significance of the anion gap is emphasized and several examples are given to illustrate a more analytic approach to using the clinical anion gap; these include disorders of low anion gap, respiratory alkalosis and pyroglutamic acidosis.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension

UniBE Contributor:

Fuster, Daniel Guido

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1521-690X

Publisher:

Bailliere Tindall

Language:

English

Submitter:

Daniel Guido Fuster

Date Deposited:

20 Jan 2016 08:02

Last Modified:

20 Jan 2016 08:02

PubMed ID:

14687589

BORIS DOI:

10.7892/boris.75283

URI:

https://boris.unibe.ch/id/eprint/75283

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