Failure Rate and Conductor Externalization of the Biotronik Linox / Sorin Vigila Implantable Cardioverter Defibrillator Lead

Noti, Fabian; Lam, Anna; Klossner, Nicole; Seiler, Jens; Servatius, Helge Simon; Medeiros Domingo, Argelia; Tran, van Nam; Häberlin, Andreas; Fuhrer, Jürg; Tanner, Hildegard; Roten, Laurent (2016). Failure Rate and Conductor Externalization of the Biotronik Linox / Sorin Vigila Implantable Cardioverter Defibrillator Lead. Heart rhythm, 13(5), pp. 1075-1082. Elsevier 10.1016/j.hrthm.2015.12.038

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BACKGROUND We observed a case of conductor externalization in a Biotronik Linox lead. OBJECTIVE To investigate lead performance of the Linox and identical Sorin Vigila lead and prevalence of conductor externalization. METHODS We compared lead performance of all Linox and Vigila leads implanted at our center (BL group; n=93) with all Boston Scientific Endotak Reliance leads (ER group; n=190) and Medtronic Sprint Quattro leads (SQ group; n=202) implanted during the same period. We screened all BL group patients for conductor externalization. RESULTS We identified 8 cases of lead failures in the BL group (index case of conductor externalization; 6 cases of non-physiological high rate sensing; one case of high voltage conductor fracture). Prospective, fluoroscopic screening of 98% of all active BL group cases revealed one additional case of conductor externalization. Median follow-up was 41, 27 and 29 months for the BL group, ER group and SQ group, respectively, lead survival 94.9%, 99.2% and 100% at 3 years, and 88%, 97.5% and 100% at 5 years (p=0.038 for BL group vs. ER group, and p=0.007 for BL group vs. SQ group by the log-rank test). Younger age at implant was an independent predictor for lead failure in the BL group (adjusted HR 0.85 [95% confidence interval 0.77-0.94]; p=0.001). CONCLUSION At our center, survival of the Linox lead is 88% at five years and significantly worse than its comparators. Conductor externalization is present in a minority of failed Linox leads. Younger age at implant is an independent predictor of Linox lead failure.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Noti, Fabian; Lam, Anna; Klossner, Nicole; Seiler, Jens; Servatius, Helge Simon; Medeiros Domingo, Argelia; Tran, van Nam; Häberlin, Andreas; Fuhrer, Jürg; Tanner, Hildegard and Roten, Laurent

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1547-5271

Publisher:

Elsevier

Language:

English

Submitter:

Helge Simon Servatius

Date Deposited:

16 Feb 2016 16:07

Last Modified:

29 Apr 2016 01:30

Publisher DOI:

10.1016/j.hrthm.2015.12.038

PubMed ID:

26738946

Uncontrolled Keywords:

Conductor externalization; Defibrillator lead; Endotak Reliance; Lead failure; Linox; Sprint Quattro

BORIS DOI:

10.7892/boris.75440

URI:

https://boris.unibe.ch/id/eprint/75440

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