Dermatomyositis in a family of Working Kelpies

Röthig, A; Rüfenacht, S; Welle, Monika Maria; Thom, N (2015). Dermatomyositis in a family of Working Kelpies. Tierärztliche Praxis. Ausgabe K - Kleintiere, Heimtiere, 43(5), pp. 331-336. Schattauer 10.15654/TPK-141112

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Eight members of a family of Working Kelpies were presented with signs compatible with dermatomyositis. Alopecia, crusts, ulcerations of the skin, depigmentation of nasal planum and lips, onychodystrophy and atrophy of the masticatory muscles were present with varying degree. Histopathology of the skin, but not from muscles was performed in three dogs and confirmed the clinical diagnosis. Different immunomodulating drugs (steroids, cyclosporine, mycophenolate mofetil, pentoxifylline, doxycyline/niacinamid, omega-3 fatty acids and vitamin E) were used with variable success. Dermatomyositis is an immune-mediated disease and a genetic predisposition is known in humans and certain canine breeds, mainly Shetland Sheepdogs and Collies, but also for the Beauceron. The responsible genes have not been identified so far. It is assumed that the Working Kelpie derives from the Collie which could explain a hereditary predisposition in the Kelpie.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > DermFocus
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Animal Pathology
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)

UniBE Contributor:

Welle, Monika Maria

Subjects:

600 Technology > 630 Agriculture

ISSN:

1434-1239

Publisher:

Schattauer

Language:

German

Submitter:

Barbara Gautschi-Steffen

Date Deposited:

15 Feb 2016 15:14

Last Modified:

24 Oct 2019 22:55

Publisher DOI:

10.15654/TPK-141112

PubMed ID:

26105578

Uncontrolled Keywords:

Ischemic dermatopathy; canine; vasculitis

BORIS DOI:

10.7892/boris.75567

URI:

https://boris.unibe.ch/id/eprint/75567

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