Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.

Huth, Markus; Ricci, A J; Cheng, A G (2011). Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection. International journal of otolaryngology, 2011(937861), p. 937861. Hindawi 10.1155/2011/937861

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Aminoglycosides are commonly prescribed antibiotics with deleterious side effects to the inner ear. Due to their popular application as a result of their potent antimicrobial activities, many efforts have been undertaken to prevent aminoglycoside ototoxicity. Over the years, understanding of the antimicrobial as well as ototoxic mechanisms of aminoglycosides has increased. These mechanisms are reviewed in regard to established and potential future targets of hair cell protection.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Huth, Markus

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1687-921X

Publisher:

Hindawi

Language:

English

Submitter:

Markus Huth

Date Deposited:

25 Jan 2016 16:11

Last Modified:

26 Jun 2016 02:10

Publisher DOI:

10.1155/2011/937861

PubMed ID:

22121370

BORIS DOI:

10.7892/boris.75574

URI:

https://boris.unibe.ch/id/eprint/75574

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