Short- and long-term efficacy and mechanism of action of tumescent suction curettage for axillary hyperhidrosis

Feldmeyer, Laurence; Bogdan, I; Moser, A; Specker, R; Kamarashev, J; French, L E; Läuchli, S (2015). Short- and long-term efficacy and mechanism of action of tumescent suction curettage for axillary hyperhidrosis. Journal of the European Academy of Dermatology and Venereology, 29(10), pp. 1933-1937. Blackwell 10.1111/jdv.13078

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BACKGROUND Axillary hyperhidrosis is a common and distressing problem interfering with the life of affected individuals. Currently, local surgery is the treatment of choice once conservative treatment has failed. OBJECTIVES To evaluate the clinical efficacy and safety of tumescent suction curettage (TSC) in treating axillary hyperhidrosis and to correlate it with histological markers. METHODS Thirty patients (17 females and 13 males, average age 29.9 years) underwent TSC. After tumescent anaesthesia, a suction cannula was inserted in the axilla on each side through two tiny incisions and subcutaneous tissue was removed by suction. We evaluated the clinical efficacy and complications, and in a subset of patients performed biopsies before surgery, as well as 1 month and 1 year after the operation. RESULTS In comparison with preoperative values, the sweat rate was diminished by 85% after 1 month, 71% after 6 months, 77% after 12 months and 61% after 24 months. The reduced efficacy with time was histologically correlated with an increase in the innervation, whereas the number of sweat glands continued to diminish. The majority of patients were satisfied with the operation but the satisfaction diminished with time. Patients with the highest preoperative sweat rates were the most satisfied after the intervention. CONCLUSION TSC is an effective and safe treatment for axillary hyperhidrosis. The long-term recurrence may be due to reinnervation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Feldmeyer, Laurence

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0926-9959

Publisher:

Blackwell

Language:

English

Submitter:

Sandra Nyffenegger

Date Deposited:

02 Mar 2016 11:59

Last Modified:

12 Sep 2017 16:27

Publisher DOI:

10.1111/jdv.13078

PubMed ID:

25771714

BORIS DOI:

10.7892/boris.76267

URI:

https://boris.unibe.ch/id/eprint/76267

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