Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study

Hamer, Mark; von Känel, Roland; Reimann, Manja; Malan, Nico T; Schutte, Alta E; Huisman, Hugo W; Malan, Leone (2015). Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study. Atherosclerosis, 238(1), pp. 52-54. Elsevier 10.1016/j.atherosclerosis.2014.11.019

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Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multi-ethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p = 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie

UniBE Contributor:

von Känel, Roland

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0021-9150

Publisher:

Elsevier

Language:

English

Submitter:

Romina Theiler

Date Deposited:

16 Mar 2016 14:46

Last Modified:

11 Feb 2021 14:10

Publisher DOI:

10.1016/j.atherosclerosis.2014.11.019

PubMed ID:

25437890

Uncontrolled Keywords:

Biomarkers; Black African; Cardiovascular disease; Epidemiology

BORIS DOI:

10.7892/boris.77022

URI:

https://boris.unibe.ch/id/eprint/77022

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