Impact of Acquired Pellicle Modification on Adhesion of Early Colonizers

Cheaib, Zeinab; Rakmathulina, Ekaterina; Lussi, Adrian; Eick, Sigrun (2015). Impact of Acquired Pellicle Modification on Adhesion of Early Colonizers. Caries research, 49(6), pp. 626-632. Karger 10.1159/000442169

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New preventive approaches against dental erosion caused by acidic drinks and beverages include fortification of beverages with natural polymers. We have shown that the mixture of casein and mucin significantly improved the erosion-inhibiting properties of the human pellicle layer. This study aimed to investigate the effect of pellicle modification by casein, mucin and a casein-mucin mixture on the adhesion of early bacterial colonizers. Test specimens of human tooth enamel were prepared, covered with saliva and coated with 0.5% aqueous (aq.) casein, 0.27% aq. mucin or with 0.5% aq. casein-0.27% aq. mucin, after which the adhesion of Streptococcus gordonii, Streptococcus oralis, and Actinomyces odontolyticus was measured after incubation for 30 min and 2 h. log10 colony-forming units were compared by nonparametric tests. All three bacterial strains adhered in higher number to pellicle-coated enamel than to native enamel. The protein modifications of pellicle all decreased the counts of adhering bacteria up to 0.34 log10/mm2, the most efficient being the casein-mucin mixture. In addition to the recently shown erosion-reducing effect by casein-mucin, modification of the pellicle may inhibit bacterial adherence compared to untreated human pellicle.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > School of Dental Medicine, Periodontics Research
04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry
04 Faculty of Medicine > School of Dental Medicine > School of Dental Medicine, Restorative Dentistry, Research

UniBE Contributor:

Cheaib, Zeinab; Lussi, Adrian and Eick, Sigrun

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0008-6568

Publisher:

Karger

Language:

English

Submitter:

Eveline Carmen Schuler

Date Deposited:

29 Mar 2016 09:19

Last Modified:

08 Sep 2017 11:13

Publisher DOI:

10.1159/000442169

PubMed ID:

26655396

Uncontrolled Keywords:

Bacterial adhesion, Casein, Dental Erosion, Mucin, Oral streptococci

BORIS DOI:

10.7892/boris.77045

URI:

https://boris.unibe.ch/id/eprint/77045

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