Diffusion-weighted imaging in musculoskeletal radiology-clinical applications and future directions

Bhojwani, Nicholas; Szpakowski, Peter; Partovi, Sasan; Maurer, Martin; Grosse, Ulrich; Von Tengg-Kobligk, Hendrik; Zipp-Partovi, Lisa; Fergus, Nathan; Kosmas, Christos; Nikolaou, Konstantin; Robbin, Mark R (2015). Diffusion-weighted imaging in musculoskeletal radiology-clinical applications and future directions. Quantitative imaging in medicine and surgery, 5(5), pp. 740-753. AME Publishing Company 10.3978/j.issn.2223-4292.2015.07.07

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Diffusion-weighted imaging (DWI) is an established diagnostic tool with regards to the central nervous system (CNS) and research into its application in the musculoskeletal system has been growing. It has been shown that DWI has utility in differentiating vertebral compression fractures from malignant ones, assessing partial and complete tears of the anterior cruciate ligament (ACL), monitoring tumor response to therapy, and characterization of soft-tissue and bone tumors. DWI is however less useful in differentiating malignant vs. infectious processes. As of yet, no definitive qualitative or quantitative properties have been established due to reasons ranging from variability in acquisition protocols to overlapping imaging characteristics. Even with these limitations, DWI can still provide clinically useful information, increasing diagnostic accuracy and improving patient management when magnetic resonance imaging (MRI) findings are inconclusive. The purpose of this article is to summarize recent research into DWI applications in the musculoskeletal system.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Maurer, Martin and Von Tengg-Kobligk, Hendrik

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2223-4292

Publisher:

AME Publishing Company

Language:

English

Submitter:

Aisha Stefania Mzinga

Date Deposited:

16 Mar 2016 16:18

Last Modified:

06 Mar 2019 10:05

Publisher DOI:

10.3978/j.issn.2223-4292.2015.07.07

PubMed ID:

26682143

Uncontrolled Keywords:

Diffusion-weighted imaging (DWI); PET/MRI; inflammatory conditions; magnetic resonance imaging (MRI); musculoskeletal neoplasms; therapy assessment

BORIS DOI:

10.7892/boris.77146

URI:

https://boris.unibe.ch/id/eprint/77146

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