Biomarkers for Hepatocellular Apoptosis in the Management of Liver Diseases

St-Pierre, Marie V; Dufour, Jean-François (2012). Biomarkers for Hepatocellular Apoptosis in the Management of Liver Diseases. Current pharmaceutical biotechnology, 13(11), pp. 2221-7. Hilversum: Bentham Science Publishers

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Apoptosis is a rare event in normal hepatocytes. However, multiple signals can trigger apoptosis in hepatocytes and it plays a role in the pathogenesis of many liver diseases. This review summarizes the mechanisms of hepatocellular apoptosis and the importance of apoptosis in the pathological processes of liver disease. The potential for non-invasive biomarkers of apoptosis to gauge the extent and follow the evolution of clinical disease is emphasized.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Dufour, Jean-François




Bentham Science Publishers




Factscience Import

Date Deposited:

04 Oct 2013 14:22

Last Modified:

06 Dec 2013 13:28

PubMed ID:


Web of Science ID:


URI: (FactScience: 213042)

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