Update Chronic Viral Hepatitis B and C

Terziroli Beretta-Piccoli, Benedetta; Schranz, Melanie; De Gottardi, Andrea; Cerny, Andreas (2015). Update Chronic Viral Hepatitis B and C. Praxis - schweizerische Rundschau für Medizin, 104(25), pp. 1393-1397. Huber 10.1024/1661-8157/a002207

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Chronic hepatitis B has a complex natural history. The age at infection, comorbidities, coinfections, and other, yet to be identified factors, determine the probability of developing a chronic infection. The HBV virus can never be completely eliminated and remains in the hepatocytes for life. However, to reach an inactive carrier status is a realistic goal of the therapy. For HBV treatment, pegylated interferon and direct antivirals are available. To screen persons at risk and to vaccinate all of the population are important prophylactic measures. Chronic hepatitis C infection leads, in 30% of cases, to liver cirrhosis. Treatment is recommended from fibrosis stage Metavir 2. New DAA allows short treatment, with a high response rate and very few adverse effects.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

UniBE Contributor:

Schranz, Melanie; De Gottardi, Andrea and Cerny, Andreas

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1661-8157

Publisher:

Huber

Language:

German

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

30 Mar 2016 11:04

Last Modified:

11 Sep 2017 20:57

Publisher DOI:

10.1024/1661-8157/a002207

PubMed ID:

26649957

Uncontrolled Keywords:

screening, vaccination, cirrhosis, hepatocellular carcinoma, DAA; Screening, Impfung, Leberzirrhose, Hepatozelluläres Karzinom, DAA

BORIS DOI:

10.7892/boris.77515

URI:

https://boris.unibe.ch/id/eprint/77515

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