Haas, Anna; Zimmermann, Kathrin; Graw, Frederik; Slack, Emma; Rusert, Peter; Ledergerber, Bruno; Bossart, Walter; Weber, Rainer; Thurnheer, Maria C; Battegay, Manuel; Hirschel, Bernard; Vernazza, Pietro; Patuto, Nicola; Macpherson, Andrew J; Günthard, Huldrych F; Oxenius, Annette; Swiss HIV Cohort Study, (2011). Systemic antibody responses to gut commensal bacteria during chronic HIV-1 infection. Gut, 60(11), pp. 1506-19. London: BMJ Publishing Group 10.1136/gut.2010.224774
Full text not available from this repository.Human systemic antibody responses to commensal microbiota are not well characterised during health and disease. Of particular interest is the analysis of their potential modulation caused by chronic HIV-1 infection which is associated with sustained enteropathy and systemic B cell disturbances reflected by impaired B cell responses and chronic B cell hyperactivity. The mechanisms underlying B cell hyperactivation and the specificities of the resulting hypergammaglobulinaemia are only poorly understood.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology |
UniBE Contributor: |
Raio, Luigi, Thurnheer Zürcher, Maria Christine, Macpherson, Andrew |
ISSN: |
0017-5749 |
Publisher: |
BMJ Publishing Group |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:22 |
Last Modified: |
05 Dec 2022 14:06 |
Publisher DOI: |
10.1136/gut.2010.224774 |
PubMed ID: |
21515549 |
Web of Science ID: |
000295399600010 |
URI: |
https://boris.unibe.ch/id/eprint/7756 (FactScience: 213082) |