Management of Home Parenteral Nutrition: A Prospective Multicenter Observational Study

Aeberhard, Carla; Leuenberger, Michèle Simone; Joray, Maya Lucia; Ballmer, Peter E; Mühlebach, Stefan; Stanga, Zeno Giovanni (2015). Management of Home Parenteral Nutrition: A Prospective Multicenter Observational Study. Annals of nutrition & metabolism, 67(4), pp. 210-217. Karger 10.1159/000440683

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BACKGROUND There are no specific Swiss home parenteral nutrition (HPN) data showing patient characteristics, quality of life (QoL) and complications. The goal of this study was to collect representative nationwide data on current adult HPN patients in Switzerland for international comparability and benchmarking. METHODS This was a multicenter, nationwide, observational study. We conducted interviews for demographics, PN characteristics, QoL and complications. The data were assessed at baseline and after a follow-up of 3 months using a questionnaire. RESULTS Thirty-three adult patients were included. The most common underlying diseases were cancer, radiation enteritis and state after bariatric surgery, and the most prevalent indication was short bowel syndrome. During the 3-month observation period, significant increase or stabilization of body weight occurred in the patients, physical activity scores improved from 34.0 to 39.4 and mental scores improved from 41.9 to 46.4. HPN dependency and traveling restrictions were of the greatest concern. Diarrhea, xerostomia and/or thirst were frequent complaints. CONCLUSION Anthropometric parameters and QoL improved during the observational period in this HPN cohort. These Swiss HPN data are prerequisite for evaluation and comparison of HPN recommendations and best clinical practice, status of professional care instructions related to HPN effectiveness, quality of treatment and patient safety.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Endocrinology, Diabetology and Clinical Nutrition

UniBE Contributor:

Leuenberger, Michèle Simone; Joray, Maya Lucia and Stanga, Zeno Giovanni

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1421-9697

Publisher:

Karger

Language:

English

Submitter:

Markus Laimer

Date Deposited:

30 Mar 2016 13:28

Last Modified:

01 Oct 2016 02:30

Publisher DOI:

10.1159/000440683

PubMed ID:

26418158

BORIS DOI:

10.7892/boris.77617

URI:

https://boris.unibe.ch/id/eprint/77617

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