Kocher, Gregor; Poulson, Jannie Lysgaard; Blichfeldt-Eckhardt, Morten Rune; Elle, Bo; Schmid, Ralph; Licht, Peter B (2015). The importance of phrenic nerve preservation and its effect on long-term postoperative lung function after pneumonectomy. European journal of cardio-thoracic surgery, 49(4), pp. 1059-1062. Oxford University Press 10.1093/ejcts/ezv334
|
Text
Kocher 2015 EJCTS the importance.pdf - Published Version Available under License Publisher holds Copyright. Download (128kB) | Preview |
OBJECTIVES
The importance of phrenic nerve preservation during pneumonectomy remains controversial. We previously demonstrated that preservation of the phrenic nerve in the immediate postoperative period preserved lung function by 3-5% but little is known about its long-term effects. We, therefore, decided to investigate the effect of temporary ipsilateral cervical phrenic nerve block on dynamic lung volumes in mid- to long-term pneumonectomy patients.
METHODS
We investigated 14 patients after a median of 9 years post pneumonectomy (range: 1-15 years). Lung function testing (spirometry) and fluoroscopic and/or sonographic assessment of diaphragmatic motion on the pneumonectomy side were performed before and after ultrasonographic-guided ipsilateral cervical phrenic nerve block by infiltration with lidocaine.
RESULTS
Ipsilateral phrenic nerve block was successfully achieved in 12 patients (86%). In the remaining 2 patients, diaphragmatic motion was already paradoxical before the nerve block. We found no significant difference on dynamic lung function values (FEV1 'before' 1.39 ± 0.44 vs FEV1 'after' 1.38 ± 0.40; P = 0.81).
CONCLUSIONS
Induction of a temporary diaphragmatic palsy did not significantly influence dynamic lung volumes in mid- to long-term pneumonectomy patients, suggesting that preservation of the phrenic nerve is of greater importance in the immediate postoperative period after pneumonectomy.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Thoraxchirurgie 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Thoracic Surgery |
UniBE Contributor: |
Kocher, Gregor, Schmid, Ralph |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1010-7940 |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Thomas Michael Marti |
Date Deposited: |
04 Apr 2016 12:13 |
Last Modified: |
15 Dec 2022 11:40 |
Publisher DOI: |
10.1093/ejcts/ezv334 |
PubMed ID: |
26405235 |
Uncontrolled Keywords: |
Diaphragm; Lung cancer; Phrenic nerve; Pneumonectomy; Pulmonary function |
BORIS DOI: |
10.7892/boris.77740 |
URI: |
https://boris.unibe.ch/id/eprint/77740 |
Actions (login required)
 |
Edit item |