New-onset epilepsy: considerations for initial and follow-up MRI to detect brain tumor

Schucht, Philippe; Duffau, Hugues (2011). New-onset epilepsy: considerations for initial and follow-up MRI to detect brain tumor. Expert review of neurotherapeutics, 11(8), pp. 1107-10. London: Expert Reviews 10.1586/ERN.11.80

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Seizures are often the presenting symptoms of a cerebral tumor and may precede its diagnosis by many years. The article under evaluation searched two large English registries for patients admitted for new-onset epilepsy. The risk of subsequently being diagnosed with a malignant brain tumor was found to be 26-fold higher compared with controls, persisted over many years and was accentuated in young patients. Recently, surgical advances have led to a significant decrease in surgical morbidities, making surgery the first treatment option for gliomas, especially low-grade gliomas. This paradigm shift warrants a consequent diagnostic workup (MRI) in patients at risk for low-grade glioma - that is, patients with new-onset epilepsy. The study is discussed in the context of the ongoing debate on neuroimaging after new-onset epilepsy.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
UniBE Contributor:	Schucht, Philippe
ISSN:	1473-7175
Publisher:	Expert Reviews
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:23
Last Modified:	05 Dec 2022 14:06
Publisher DOI:	10.1586/ERN.11.80
PubMed ID:	21797650
Web of Science ID:	000294650400009
URI:	https://boris.unibe.ch/id/eprint/7816 (FactScience: 213158)