The role of patch testing in the management of oral lichenoid reactions.

Suter, Valérie; Warnakulasuriya, Saman (2016). The role of patch testing in the management of oral lichenoid reactions. Journal of oral pathology & medicine, 45(1), pp. 48-57. Wiley 10.1111/jop.12328

[img] Text
The role of patch testing.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (654kB) | Request a copy

BACKGROUND AND OBJECTIVES The distinction of oral lichenoid reactions from oral lichen planus may be difficult in a clinical setting. Our aims were to ascertain the utility of patch testing to confirm the association of oral lichenoid reactions with dental restorations and to identify the benefits of replacement of restorations, primarily made of amalgam. METHODS Patients seen in an oral medicine unit over a 10-year period diagnosed with oral lichenoid reactions, with oral lichen planus resistant to treatment or with atypical lichenoid features were included in this study. All had been subjected to skin patch testing. Histopathology reports blinded to patch test results were scrutinized. Patch-test-positive subjects were advised to have their restorations replaced. All were followed up to determine disease resolution for at least 3 months thereafter. RESULTS Among 115 patients, 67.8% patients reacted positive to a dental material and nearly a quarter to mercury or amalgam. No correlation was found between pathology and skin patch testing results (P = 0.44). A total of 87 patients were followed up in clinic, and among 26 patch-test-positive patients who had their amalgam fillings replaced, moderate to complete resolution was noted in 81%. CONCLUSIONS Skin patch testing is a valuable tool to confirm clinically suspected oral lichenoid reactions. Pathology diagnoses of oral lichenoid reactions did not correlate with patch test results. Prospective studies are needed to ascertain that a clinically suspected oral lichenoid reaction with a positive patch test result may resolve after the replacement of amalgam fillings.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology

UniBE Contributor:

Suter, Valérie

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0904-2512

Publisher:

Wiley

Language:

English

Submitter:

Eveline Carmen Schuler

Date Deposited:

15 Apr 2016 13:42

Last Modified:

12 Sep 2017 23:31

Publisher DOI:

10.1111/jop.12328

PubMed ID:

25990286

Uncontrolled Keywords:

amalgam, dental restorative materials, mercury, oral lichen planus, oral lichenoid reactions, patch test

BORIS DOI:

10.7892/boris.78504

URI:

https://boris.unibe.ch/id/eprint/78504

Actions (login required)

Edit item Edit item
Provide Feedback