Depression as a risk factor for acute coronary syndrome: a review.

Misteli, Genny S; Stute, Petra (2015). Depression as a risk factor for acute coronary syndrome: a review. Archives of gynecology and obstetrics, 291(6), pp. 1213-1220. Springer 10.1007/s00404-015-3618-0

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PURPOSE In the past few years more and more research focused on psychosocial risk factors of cardiovascular disease, including depression. This review focuses on depression as a long-term risk factor for acute coronary syndrome in initially heart disease-free people. METHODS The studies included (n = 15) comprised people without heart disease who were exposed to depression. The outcome was acute coronary syndrome (acute myocardial infarction, instable angina pectoris, sudden cardiac death). Only articles published in English between 2000 and 2013 were considered. RESULTS Most but not all studies found an association between depression and cardiac outcome. Possible explanations for the inconsistency of the findings are discussed. CONCLUSIONS Most likely there is an association between depression and acute coronary syndrome. However, it remains unclear whether depression acts as an independent risk factor for developing an acute coronary syndrome, or if depression promotes the development of an acute coronary syndrome by indirect means.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology

UniBE Contributor:

Stute, Petra

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0932-0067

Publisher:

Springer

Language:

English

Submitter:

Monika Zehr

Date Deposited:

05 Apr 2016 13:56

Last Modified:

10 Nov 2016 17:48

Publisher DOI:

10.1007/s00404-015-3618-0

PubMed ID:

25600445

BORIS DOI:

10.7892/boris.78627

URI:

https://boris.unibe.ch/id/eprint/78627

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