Everolimus-Eluting Bioresorbable Vascular Scaffold System in the Treatment of Cardiac Allograft Vasculopathy: the CART (Cardiac Allograft Reparative Therapy) Prospective Multicenter Pilot Study.

Pighi, Michele; Tomai, Fabrizio; Petrolini, Alessandro; de Luca, Leonardo; Tarantini, Giuseppe; Barioli, Alberto; Colombo, Paola; Klugmann, Silvio; Ferlini, Marco; Ormezzano, Maurizio Ferrario; Loi, Bruno; Calabrò, Paolo; Bianchi, Renato Maria; Faggian, Giuseppe; Forni, Alberto; Vassanelli, Corrado; Valgimigli, Marco; Ribichini, Flavio (2015). Everolimus-Eluting Bioresorbable Vascular Scaffold System in the Treatment of Cardiac Allograft Vasculopathy: the CART (Cardiac Allograft Reparative Therapy) Prospective Multicenter Pilot Study. Journal of cardiovascular translational research JCTR, 9(1), pp. 40-48. Springer 10.1007/s12265-015-9665-x

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Cardiac allograft vasculopathy (CAV) is a form of accelerated atherosclerosis, which represents the leading cause of late morbidity and mortality after heart transplantation. The recent bioresorbable vascular scaffold (BVS) technology represents a potential novel therapeutic tool, in the context of CAV, by allowing transient scaffolding and concomitant vessel healing. Eligible subjects will be treated by using the Absorb Everolimus-Eluting BVS (Abbott Vascular, Santa Clara, CA, USA), and evaluated at pre-determined time points, up to 3 years since the index procedure. Both clinical and imaging data will be collected in dedicated case report forms (CRF). All imaging data will be analyzed in an independent core laboratory. The primary aim of the study is to evaluate the angiographic performance at 1 year of second-generation Absorb BVS, in heart transplant recipients affected by CAV.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Valgimigli, Marco

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1937-5387

Publisher:

Springer

Language:

English

Submitter:

Daria Vogelsang

Date Deposited:

20 Apr 2016 11:14

Last Modified:

20 Apr 2016 11:14

Publisher DOI:

10.1007/s12265-015-9665-x

PubMed ID:

26684009

Uncontrolled Keywords:

Cardiac allograft vasculopathy, Everolimus-eluting bioresorbable vascular scaffold, Heart transplant

URI:

https://boris.unibe.ch/id/eprint/78809

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