Helbling, Rossana; Lava, Sebastiano; Simonetti, Giacomo; Camozzi, Pietro; Bianchetti, Mario G; Milani, Gregorio P (2016). Gallbladder and Pancreas in Henoch-Schönlein Purpura: Review of the Literature. Journal of pediatric gastroenterology and nutrition, 62(3), pp. 457-461. Lippincott Williams & Wilkins 10.1097/MPG.0000000000000955
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OBJECTIVE
Involvement of the pancreato-biliary system has been occasionally noted in Henoch-Schönlein purpura. Furthermore, cases of this vasculitis syndrome sometimes develop in the context of a viral hepatitis or after hepatitis vaccination.
METHODS
We completed a review of the literature.
RESULTS
Fifty reports published between 1977 and 2015 were retained for the analysis. A pancreato-biliary involvement was recognized in 34 individually well-described patients (♂:♀ = 19:15) with severe abdominal pain: pancreatitis (N = 20), acalculous cholecystitis (N = 11), both pancreatitis and cholecystitis (N = 3). In all of the pancreatitis patients, full recovery occurred (within ≤3 weeks in three-fourths of the patients). Cholecystectomy was performed in 8 cholecystitis patients. Seventeen Henoch-Schönlein patients (♂:♀ = 9:8) were associated with a viral liver disease and 4 (♂:♀ = 1:3) with a hepatitis vaccination. The vasculitis syndrome rapidly remitted in the 7 patients accompanying hepatitis A or E, in 2 patients of hepatitis B, and in the 4 patients preceded by a vaccination. Henoch-Schönlein purpura seemed to be serious in 5 patients with chronic hepatitis B and in 3 with chronic hepatitis C.
CONCLUSIONS
This analysis indicates that pancreato-biliary involvement is unusual in Henoch-Schönlein purpura. This complication deserves consideration in patients with especially severe abdominal pain. Finally, viral hepatitides and hepatitis vaccinations seem to be rare triggers of Henoch-Schönlein purpura.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension 04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine |
UniBE Contributor: |
Lava, Sebastiano, Simonetti, Giacomo |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0277-2116 |
Publisher: |
Lippincott Williams & Wilkins |
Language: |
English |
Submitter: |
Anette van Dorland |
Date Deposited: |
02 May 2016 10:29 |
Last Modified: |
05 Dec 2022 14:53 |
Publisher DOI: |
10.1097/MPG.0000000000000955 |
PubMed ID: |
26308313 |
BORIS DOI: |
10.7892/boris.79296 |
URI: |
https://boris.unibe.ch/id/eprint/79296 |
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