Breastfeeding-Associated Hypernatremia: A Systematic Review of the Literature.

Lavagno, Camilla; Camozzi, Pietro; Renzi, Samuele; Lava, Sebastiano; Simonetti, Giacomo; Bianchetti, Mario G; Milani, Gregorio P (2016). Breastfeeding-Associated Hypernatremia: A Systematic Review of the Literature. Journal of human lactation, 32(1), pp. 67-74. 10.1177/0890334415613079

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There are increasing reports on hypernatremia, a potentially devastating condition, in exclusively breastfed newborn infants. Our purposes were to describe the clinical features of the condition and identify the risk factors for it. We performed a review of the existing literature in the National Library of Medicine database and in the search engine Google Scholar. A total of 115 reports were included in the final analysis. Breastfeeding-associated neonatal hypernatremia was recognized in infants who were ≤ 21 days of age and had ≥ 10% weight loss of birth weight. Cesarean delivery, primiparity, breast anomalies or breastfeeding problems, excessive prepregnancy maternal weight, delayed first breastfeeding, lack of previous breastfeeding experience, and low maternal education level were significantly associated with breastfeeding-associated hypernatremia. In addition to excessive weight loss (≥ 10%), the following clinical findings were observed: poor feeding, poor hydration state, jaundice, excessive body temperature, irritability or lethargy, decreased urine output, and epileptic seizures. In conclusion, the present survey of the literature identifies the following risk factors for breastfeeding-associated neonatal hypernatremia: cesarean delivery, primiparity, breastfeeding problems, excessive maternal body weight, delayed breastfeeding, lack of previous breastfeeding experience, and low maternal education level.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Lava, Sebastiano, Simonetti, Giacomo

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1552-5732

Language:

English

Submitter:

Anette van Dorland

Date Deposited:

27 Apr 2016 13:01

Last Modified:

05 Dec 2022 14:53

Publisher DOI:

10.1177/0890334415613079

PubMed ID:

26530059

Uncontrolled Keywords:

breastfeeding, dehydration, hypernatremia, newborn infant, review

URI:

https://boris.unibe.ch/id/eprint/79297

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