Long-term results of endoscopic third ventriculostomy: an outcome analysis.

Vulcu, Sonja; Eickele, Leonie; Cinalli, Giuseppe; Wagner, Wolfgang; Oertel, Joachim (2015). Long-term results of endoscopic third ventriculostomy: an outcome analysis. Journal of neurosurgery, 123(6), pp. 1456-1462. American Association of Neurological Surgeons 10.3171/2014.11.JNS14414

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OBJECT Endoscopic third ventriculostomy (ETV) is the procedure of choice in the treatment of obstructive hydrocephalus. The excellent clinical and radiological success rates are well known. Nevertheless, very few papers have addressed the very long term outcomes of the procedure in very large series. The authors present a large case series of 113 patients who underwent 126 ETVs, and they highlight the initial postoperative outcome after 3 months and long-term follow-up with an average of 7 years. METHODS All patients who underwent ETV at the Department of Neurosurgery, Mainz University Hospital, between 1993 and 1999 were evaluated. Obstructive hydrocephalus was the causative pathology in all cases. RESULTS The initial clinical success rate was 82% and decreased slightly to 78% during long-term follow-up. Long-term success was analyzed using Kaplan-Meier curves. Overall, ETV failed in 31 patients. These patients underwent a second ETV or shunt treatment. A positive impact on long-term success was seen for age older than 6 months, and for obstruction due to cysts or benign aqueductal stenosis. The complication rate was 9% with 5 intraoperative and 5 postoperative events. CONCLUSIONS The high clinical success rate in short-term and long-term follow-up confirms ETV's status as the gold standard for the treatment of obstructive hydrocephalus, especially for distinct pathologies. The patient's age and underlying pathology may influence the outcome. These factors should be considered carefully preoperatively by the surgeon.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery

UniBE Contributor:

Vulcu, Sonja


600 Technology > 610 Medicine & health




American Association of Neurological Surgeons




Nicole Söll

Date Deposited:

12 Apr 2016 11:01

Last Modified:

12 Apr 2016 11:01

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

ETV = endoscopic third ventriculostomy; brain; endoscopic third ventriculostomy; hydrocephalus; long-term results; neuroendoscopy





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