MicroRNA-381 Represses ID1 and is Deregulated in Lung Adenocarcinoma

Rothschild, Sacha I; Tschan, Mario P; Jaggi, Rolf; Fey, Martin F; Gugger, Mathias; Gautschi, Oliver (2012). MicroRNA-381 Represses ID1 and is Deregulated in Lung Adenocarcinoma. Journal of thoracic oncology, 7(7), pp. 1069-77. Hagerstown, Md.: Wolters Kluwer Health/Lippincott Williams & Wilkins 10.1097/JTO.0b013e31824fe976

Full text not available from this repository. (Request a copy)

MicroRNAs are small, noncoding RNAs that suppress gene expression by binding to the 3' untranslated region (UTR) and thereby repress translation or decrease messenger RNA stability. Inhibitor of differentiation 1 (ID1) is a putative stem-cell gene involved in invasion and angiogenesis. We previously showed that ID1 is regulated by Src kinases, overexpressed in human lung adenocarcinoma, and targeted by Src-dependent microRNAs. The current study focused on the association between miR-381 and ID1 in lung adenocarcinoma.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Pathologie > Forschungsgruppe Molekularbiologie
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Tschan, Mario; Jaggi, Rolf; Fey, Martin and Gugger, Mathias




Wolters Kluwer Health/Lippincott Williams & Wilkins




Factscience Import

Date Deposited:

04 Oct 2013 14:23

Last Modified:

17 Mar 2015 21:02

Publisher DOI:


PubMed ID:


Web of Science ID:



https://boris.unibe.ch/id/eprint/8067 (FactScience: 213522)

Actions (login required)

Edit item Edit item
Provide Feedback