[Hand transplantation - fiction or reality?]

Vögelin, Esther (2011). [Hand transplantation - fiction or reality?]. Therapeutische Umschau, 68(12), pp. 730-4. Bern: Huber 10.1024/0040-5930/a000237

Full text not available from this repository.

Hand transplantation has been indicated in selective patients after traumatic upper extremity amputation and only performed in a few centers around the world for the last decade. In comparison to solid organ transplantation, there is a challenge to overcome the host immunological barrier due to complex antigenicity of the different included tissues, the skin being the most susceptible to rejection. Patients require lifelong immunosuppression for non life-threatening conditions. Minimization of maintenance immunosuppression represents the key step for promoting wider applicability of hand transplantation. Current research is working towards the understanding mechanisms of composite tissue allograft (CTA) rejection. Worldwide, in 51 patients 72 hands (21 double hand transplants) and once both arms have been successfully transplanted since 1998.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Orthopaedic, Plastic and Hand Surgery (DOPH) > Clinic of Plastic and Hand Surgery > Hand Surgery
UniBE Contributor:	Vögelin, Esther
ISSN:	0040-5930
Publisher:	Huber
Language:	German
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:23
Last Modified:	05 Dec 2022 14:06
Publisher DOI:	10.1024/0040-5930/a000237
PubMed ID:	22139989
URI:	https://boris.unibe.ch/id/eprint/8095 (FactScience: 213569)