Dill, Michael T; Rothweiler, Sonja; Djonov, Valentin; Hlushchuk, Ruslan; Tornillo, Luigi; Terracciano, Luigi; Meili-Butz, Silvia; Radtke, Freddy; Heim, Markus H; Semela, David (2012). Disruption of Notch1 induces vascular remodeling, intussusceptive angiogenesis, and angiosarcomas in livers of mice. Gastroenterology, 142(4), 967-977.e2. Philadelphia, Pa.: Elsevier 10.1053/j.gastro.2011.12.052
Full text not available from this repository.Notch signaling mediates embryonic vascular development and normal vascular remodeling; Notch1 knockout mice develop nodular regenerative hyperplasia (NRH). The pathogenesis of NRH is unclear, but has been associated with vascular injury in the liver sinusoids in clinical studies. We investigated the role of Notch1 signaling in liver sinusoidal endothelial cells (LSECs).
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy |
UniBE Contributor: |
Djonov, Valentin Georgiev, Hlushchuk, Ruslan |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0016-5085 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:23 |
Last Modified: |
05 Dec 2022 14:06 |
Publisher DOI: |
10.1053/j.gastro.2011.12.052 |
PubMed ID: |
22245843 |
Web of Science ID: |
000302296400046 |
URI: |
https://boris.unibe.ch/id/eprint/8132 (FactScience: 213617) |
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