Influence of previous surgery on patient-rated outcome after surgery for degenerative disorders of the lumbar spine.

Zehnder, Pascal; Aghayev, Emin; Fekete, Tamas F; Haschtmann, Daniel; Pigott, Tim; Mannion, Anne F (2016). Influence of previous surgery on patient-rated outcome after surgery for degenerative disorders of the lumbar spine. European spine journal, 25(8), pp. 2553-2562. Springer 10.1007/s00586-016-4383-x

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PURPOSE Few studies have used multivariate models to quantify the effect of multiple previous spine surgeries on patient-oriented outcome after spine surgery. This study sought to quantify the effect of prior spine surgery on 12-month postoperative outcomes in patients undergoing surgery for different degenerative disorders of the lumbar spine. METHODS The study included 4940 patients with lumbar degenerative disease documented in the Spine Tango Registry of EUROSPINE, the Spine Society of Europe, from 2004 to 2015. Preoperatively and 12 months postoperatively, patients completed the multidimensional Core Outcome Measures Index (COMI; 0-10 scale). Patients' medical history and surgical details were recorded using the Spine Tango Surgery 2006 and 2011 forms. Multiple linear regression models were used to investigate the relationship between the number of previous surgeries and the 12-month postoperative COMI score, controlling for the baseline COMI score and other potential confounders. RESULTS In the adjusted model including all cases, the 12-month COMI score showed a 0.37-point worse value [95 % confidence intervals (95 % CI) 0.29-0.45; p < 0.001] for each additional prior spine surgery. In the subgroup of patients with lumbar disc herniation, the corresponding effect was 0.52 points (95 % CI 0.27-0.77; p < 0.001) and in lumbar degenerative spondylolisthesis, 0.40 points (95 % CI 0.17-0.64; p = 0.001). CONCLUSIONS We were able to demonstrate a clear "dose-response" effect for previous surgery: the greater the number of prior spine surgeries, the systematically worse the outcome at 12 months' follow-up. The results of this study can be used when considering or consenting a patient for further surgery, to better inform the patient of the likely outcome and to set realistic expectations.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Evaluative Research into Orthopaedic Surgery
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Aghayev, Emin

Subjects:

300 Social sciences, sociology & anthropology > 360 Social problems & social services
600 Technology > 610 Medicine & health

ISSN:

0940-6719

Publisher:

Springer

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

03 May 2016 15:08

Last Modified:

22 Jan 2020 12:01

Publisher DOI:

10.1007/s00586-016-4383-x

PubMed ID:

26801193

Uncontrolled Keywords:

COMI; Degenerative disorders of the lumbar spine; Patient-rated outcome; Previous surgery; Spine; Tango

BORIS DOI:

10.7892/boris.81906

URI:

https://boris.unibe.ch/id/eprint/81906

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