Rhesus factors and ammonium: a function in efflux?

Ludewig, Uwe; von Wirén, Nico; Rentsch, Doris; Frommer, Wolf B. (2001). Rhesus factors and ammonium: a function in efflux? Genome biology and evolution, 2(3), pp. 1-5. Oxford University Press 10.1186/gb-2001-2-3-reviews1010

Preview

Text GenomeBiol_2001.pdf - Published Version Available under License Publisher holds Copyright. Download (85kB) | Preview

Completion of fungal, plant and human genomes paved the way to the identification of erythrocytic rhesus proteins and their kidney homologs as ammonium transporters.

Ammonium is the preferred nitrogen source of bacteria and fungi, and plants acquire nitrogen from the soil in the form of ammonium [1]. In animals and humans, assimilated forms of nitrogen - amino acids - are much preferred for nutrition, and, in the case of ammonotelic animals, ammonium is used for the excretion of nitrogen instead. In the human kidney, ammonium is produced, reabsorbed and excreted as a means to maintain pH balance and to get rid of surplus inorganic nitrogen. Whether ammonium transport also has a role in the pH regulation of other organs is not known and the molecular mechanisms were not, up to now, understood.

Interest & Impact

Downloads

231 since deposited on 02 Jun 2016
23 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item