Sensitive and rapid detection of ganciclovir resistance by PCR based MALDI-TOF analysis

Zürcher, Samuel; Mooser, Catherine; Lüthi, Alexander Urs; Mühlemann, Kathrin; Barbani, Maria Teresa; Mohacsi, Paul; Garzoni, Christian; Gorgievski-Hrisoho, Meri; Schaller, André; Flatz, Lukas (2012). Sensitive and rapid detection of ganciclovir resistance by PCR based MALDI-TOF analysis. Journal of clinical virology, 54(4), pp. 359-63. Amsterdam: Elsevier 10.1016/j.jcv.2012.04.019

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Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in transplant recipients. Resistance against ganciclovir is increasingly observed. According to current guidelines, direct drug resistance testing is not always performed due to high costs and work effort, even when resistance is suspected.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Zürcher, Samuel; Mooser, Catherine; Lüthi, Alexander; Mühlemann, Kathrin; Barbani, Maria Teresa; Mohacsi, Paul; Garzoni, Christian; Gorgievski, Meri and Schaller, André

ISSN:

1386-6532

ISBN:

1386-6532

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:24

Last Modified:

06 Dec 2013 13:29

Publisher DOI:

10.1016/j.jcv.2012.04.019

PubMed ID:

22633201

Web of Science ID:

000306374700015

Additional Information:

Zuercher, Samuel Mooser, Catherine Luethi, Alexander Urs Muehlemann, Kathrin Barbani, Maria Teresa Mohacsi, Paul Garzoni, Christian Gorgievski-Hrisoho, Meri Schaller, Andre Flatz, Lukas

URI:

https://boris.unibe.ch/id/eprint/8318 (FactScience: 213837)

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