Voriconazole-induced phototoxicity in children

Bernhard, Sara; Kernland Lang, Kristin; Ammann, Roland A; Lüer, Sonja; Leibundgut, Kurt; Diepold, Miriam; Aebi, Christoph (2012). Voriconazole-induced phototoxicity in children. Pediatric infectious disease journal, 31(7), pp. 769-71. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1097/INF.0b013e3182566311

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Voriconazole is used in antifungal prophylaxis. We performed a retrospective review of immunocompromised children receiving prophylaxis with voriconazole during major hospital renovation, who developed phototoxic skin reactions. The overall incidence of phototoxic skin reactions was 33%. A voriconazole dose of ≥6 mg/kg of body weight per dose twice daily was associated with a significantly greater risk to develop phototoxic skin reactions compared with lower doses.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine

UniBE Contributor:

Kernland Lang, Kristin Helene; Ammann, Roland; Lüer, Sonja Christina; Leibundgut, Kurt; Diepold, Miriam and Aebi, Christoph

ISSN:

0891-3668

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:24

Last Modified:

06 Dec 2013 13:29

Publisher DOI:

10.1097/INF.0b013e3182566311

PubMed ID:

22517339

Web of Science ID:

000305708300025

URI:

https://boris.unibe.ch/id/eprint/8339 (FactScience: 213865)

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