Harada, Y; Bhat, P; Munk, Marion; Goldstein, DA (2017). Changes in Scleral Architecture in Chronic Vogt-Koyanagi-Harada Disease. Ocular immunology and inflammation, 25(1), pp. 85-92. Informa Healthcare 10.3109/09273948.2015.1057600
Full text not available from this repository.PURPOSE:
To describe scleral changes in chronic VKH.
METHODS:
Medical records of patients with chronic VKH were retrospectively reviewed. Change of scleral architecture was defined as progressive posterior bowing on OCT, axial length elongation, and/or increased myopia more than -1.0 D, not explicable by other etiologies.
RESULTS:
In total, 28 eyes (16 patients) with mean age of disease onset 32.5 ± 14.0 years were included in the study. Disease duration was 15.1 ± 10.2 years. Eight eyes (28.6%) showed progressive scleral architectural changes. Five eyes (18%) developed scleral changes on OCT, not seen on prior imaging (2-12 years earlier). One eye had posterior bowing on OCT with increased axial length, both eyes of a bilateral pseudophake developed increased myopia with increased axial length. Well-circumscribed chorioretinal atrophy within the arcade was associated with progressive scleral change.
CONCLUSIONS:
Progressive scleral change may develop as a late complication of VKH. The association with well-circumscribed chorioretinal atrophy suggests that chronic choroidal inflammation may be responsible.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Munk, Marion |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0927-3948 |
Publisher: |
Informa Healthcare |
Language: |
English |
Submitter: |
Marion Munk |
Date Deposited: |
28 Jun 2016 09:59 |
Last Modified: |
05 Dec 2022 14:56 |
Publisher DOI: |
10.3109/09273948.2015.1057600 |
PubMed ID: |
26645360 |
URI: |
https://boris.unibe.ch/id/eprint/83438 |
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