Acute, posterior multifocal placoid pigment epitheliopathy: a case of 11 recurrences over 15 years

Cohen, LM; Munk, Marion; Goldstein, DA; Jampol, LM (2015). Acute, posterior multifocal placoid pigment epitheliopathy: a case of 11 recurrences over 15 years. Retinal Cases & Brief Reports, 9(3), pp. 226-230. Lippincott Williams & Wilkins 10.1097/ICB.0000000000000145

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PURPOSE: To report the case of a patient with recurrent, acute posterior multifocal placoid pigment epitheliopathy. To the best of our knowledge, this is the longest documented course with the greatest number of recurrences reported. METHODS: Observational case report of one patient. A 27-year-old otherwise healthy male patient presented with recurrence of new scotomata over 15 years. Fundus photography, fluorescein angiography, indocyanine green angiography, fundus autofluorescence, and optical coherence tomography documented his clinical course. RESULTS: Over the course of 15 years, the patient developed 11 symptomatic (5 imaging-documented) recurrences of acute, posterior multifocal placoid pigment epitheliopathy affecting both eyes. Each episode manifested with new subjective scotomata and new lesions noted on imaging. Symptoms mostly resolved after each episode, and visual outcome remained excellent (20/20 in the right eye and 20/25 left eye at the last follow-up). CONCLUSION: Although typically monophasic, acute posterior multifocal placoid pigment epitheliopathy can rarely present with a recurrent course over a prolonged period of time and should be considered as a diagnosis in patients presenting with recurrent visual symptoms and new placoid lesions on imaging. In recurrent cases, visual recovery may still remain excellent.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Munk, Marion

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1935-1089

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Marion Munk

Date Deposited:

22 Jun 2016 17:52

Last Modified:

04 Nov 2016 11:32

Publisher DOI:

10.1097/ICB.0000000000000145

PubMed ID:

25741634

URI:

https://boris.unibe.ch/id/eprint/83440

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