Haeberlin, Andreas; Lacheta, Lucca; Niederhauser, Thomas; Marisa, Thanks; Wildhaber, Reto A; Goette, Josef; Jacomet, Marcel; Seiler, Jens; Fuhrer, Jürg; Roten, Laurent; Tanner, Hildegard; Vogel, Rolf (2016). Markers for silent atrial fibrillation in esophageal long-term electrocardiography. Journal of electrocardiology, 49(4), pp. 496-503. Elsevier 10.1016/j.jelectrocard.2016.03.006
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PURPOSE
Paroxysmal atrial fibrillation (PAF) often remains undiagnosed. Long-term surface ECG is used for screening, but has limitations. Esophageal ECG (eECG) allows recording high quality atrial signals, which were used to identify markers for PAF.
METHODS
In 50 patients (25 patients with PAF; 25 controls) an eECG and surface ECG was recorded simultaneously. Partially A-V blocked atrial runs (PBARs) were quantified, atrial signal duration in eECG was measured.
RESULTS
eECG revealed 1.8‰ of atrial premature beats in patients with known PAF to be PBARs with a median duration of 853ms (interquartile range (IQR) 813-1836ms) and a median atrial cycle length of 366ms (IQR 282-432ms). Even during a short recording duration of 2.1h (IQR 1.2-17.2h), PBARs occurred in 20% of PAF patients but not in controls (p=0.05). Left atrial signal duration was predictive for PAF (72% sensitivity, 80% specificity).
CONCLUSIONS
eECG reveals partially blocked atrial runs and prolonged left atrial signal duration - two novel surrogate markers for PAF.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE) 04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Häberlin, Andreas David Heinrich, Marisa, Thanks, Fuhrer, Jürg (A), Roten, Laurent, Tanner, Hildegard |
Subjects: |
600 Technology > 610 Medicine & health 500 Science > 570 Life sciences; biology 600 Technology 600 Technology > 620 Engineering |
ISSN: |
1532-8430 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Andreas Häberlin |
Date Deposited: |
14 Jul 2016 16:40 |
Last Modified: |
29 Mar 2023 23:34 |
Publisher DOI: |
10.1016/j.jelectrocard.2016.03.006 |
PubMed ID: |
27016257 |
Uncontrolled Keywords: |
atrial fibrillation; esophageal ECG; long-term ECG; surrogate markers |
BORIS DOI: |
10.7892/boris.83499 |
URI: |
https://boris.unibe.ch/id/eprint/83499 |
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