Markers for silent atrial fibrillation in esophageal long-term electrocardiography.

Häberlin, Andreas; Lacheta, Lucca; Niederhauser, Thomas; Marisa, Thanks; Wildhaber, Reto A; Goette, Josef; Jacomet, Marcel; Seiler, Jens; Fuhrer, Jürg; Roten, Laurent; Tanner, Hildegard; Vogel, Rolf (2016). Markers for silent atrial fibrillation in esophageal long-term electrocardiography. Journal of electrocardiology, 49(4), pp. 496-503. Elsevier 10.1016/j.jelectrocard.2016.03.006

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PURPOSE Paroxysmal atrial fibrillation (PAF) often remains undiagnosed. Long-term surface ECG is used for screening, but has limitations. Esophageal ECG (eECG) allows recording high quality atrial signals, which were used to identify markers for PAF. METHODS In 50 patients (25 patients with PAF; 25 controls) an eECG and surface ECG was recorded simultaneously. Partially A-V blocked atrial runs (PBARs) were quantified, atrial signal duration in eECG was measured. RESULTS eECG revealed 1.8‰ of atrial premature beats in patients with known PAF to be PBARs with a median duration of 853ms (interquartile range (IQR) 813-1836ms) and a median atrial cycle length of 366ms (IQR 282-432ms). Even during a short recording duration of 2.1h (IQR 1.2-17.2h), PBARs occurred in 20% of PAF patients but not in controls (p=0.05). Left atrial signal duration was predictive for PAF (72% sensitivity, 80% specificity). CONCLUSIONS eECG reveals partially blocked atrial runs and prolonged left atrial signal duration - two novel surrogate markers for PAF.

Item Type:

Journal Article (Original Article)

Division/Institute:

10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE)
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Häberlin, Andreas; Marisa, Thanks; Fuhrer, Jürg; Roten, Laurent and Tanner, Hildegard

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology
600 Technology
600 Technology > 620 Engineering

ISSN:

1532-8430

Publisher:

Elsevier

Language:

English

Submitter:

Andreas Häberlin

Date Deposited:

14 Jul 2016 16:40

Last Modified:

21 Jun 2017 10:58

Publisher DOI:

10.1016/j.jelectrocard.2016.03.006

PubMed ID:

27016257

Uncontrolled Keywords:

atrial fibrillation; esophageal ECG; long-term ECG; surrogate markers

BORIS DOI:

10.7892/boris.83499

URI:

https://boris.unibe.ch/id/eprint/83499

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