Engisch, Renate; Titelbaum, David S; Chilver-Stainer, Lara; Kellner-Weldon, Frauke (2016). Susac's syndrome: Leptomeningeal enhancement on 3D FLAIR MRI. Multiple sclerosis journal, 22(7), pp. 972-974. Sage 10.1177/1352458516636836
Full text not available from this repository.BACKGROUND
Contrast-enhanced (ce) fluid-attenuated inversion recovery magnetic resonance imaging (FLAIR MRI) has recently been shown to identify leptomeningeal pathology in multiple sclerosis.
OBJECTIVE
To demonstrate leptomeningeal enhancement on three-dimensional (3D) FLAIR in a case of Susac's syndrome.
METHODS
Leptomeningeal enhancement was correlated with clinical activity over 20 months and compared to retinal fluorescein angiography.
RESULTS
The size, number, and location of leptomeningeal enhancement varied over time and generally correlated with symptom severity. The appearance was remarkably similar to that of retinal vasculopathy.
CONCLUSION
Ce 3D FLAIR may aid in diagnosis and understanding of pathophysiology in Susac's syndrome and may serve as a biomarker for disease activity.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Engisch, Renate, Chilver-Stainer, Lara, Kellner-Weldon, Frauke |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1352-4585 |
Publisher: |
Sage |
Language: |
English |
Submitter: |
Martin Zbinden |
Date Deposited: |
18 Jul 2016 16:40 |
Last Modified: |
05 Dec 2022 14:56 |
Publisher DOI: |
10.1177/1352458516636836 |
PubMed ID: |
27207452 |
Uncontrolled Keywords: |
Susac’s syndrome; contrast-enhanced FLAIR; leptomeningeal pathology |
URI: |
https://boris.unibe.ch/id/eprint/83715 |
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