In vivo imaging enters parasitology

Heussler, Volker; Doerig, Christian (2006). In vivo imaging enters parasitology. Trends in parasitology, 22(5), pp. 192-195. Elsevier Current Trends 10.1016/j.pt.2006.03.001

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In vivo infection routes of parasites have remained something of a "black box", in which only snapshot views of fixed tissues are available. Clearly, there exists a strong need for imaging approaches to visualise living parasites within intact organs and animals. In vivo imaging of fluorescent Plasmodium parasites now provides us with exciting insights into the infection process, from the bite of the infected mosquito to the invasion of liver cells, and alternative approaches using luciferase-expressing parasites have been used to monitor their dissemination in mice. This rapidly developing field will go a long way towards deepening our understanding of host-parasite interactions at different levels.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Cell Biology > Malaria
08 Faculty of Science > Department of Biology > Institute of Cell Biology

UniBE Contributor:

Heussler, Volker

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

1471-4922

Publisher:

Elsevier Current Trends

Language:

English

Submitter:

Volker Heussler

Date Deposited:

06 Jul 2016 11:30

Last Modified:

07 Jul 2016 04:35

Publisher DOI:

10.1016/j.pt.2006.03.001

PubMed ID:

16545613

BORIS DOI:

10.7892/boris.84075

URI:

https://boris.unibe.ch/id/eprint/84075

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