Effects of Alzheimer's Disease on Visual Target Detection: A "Peripheral Bias"

Vallejo, Vanessa; Cazzoli, Dario; Rampa, Luca; Zito, Giuseppe Angelo; Feuerstein, Flurin; Gruber, Nicole; Müri, René Martin; Mosimann, Urs Peter; Nef, Tobias (2016). Effects of Alzheimer's Disease on Visual Target Detection: A "Peripheral Bias". Frontiers in aging neuroscience, 8(200), p. 200. Frontiers Research Foundation 10.3389/fnagi.2016.00200

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Visual exploration is an omnipresent activity in everyday life, and might represent an important determinant of visual attention deficits in patients with Alzheimer's Disease (AD). The present study aimed at investigating visual search performance in AD patients, in particular target detection in the far periphery, in daily living scenes. Eighteen AD patients and 20 healthy controls participated in the study. They were asked to freely explore a hemispherical screen, covering ±90°, and to respond to targets presented at 10°, 30°, and 50° eccentricity, while their eye movements were recorded. Compared to healthy controls, AD patients recognized less targets appearing in the center. No difference was found in target detection in the periphery. This pattern was confirmed by the fixation distribution analysis. These results show a neglect for the central part of the visual field for AD patients and provide new insights by mean of a search task involving a larger field of view.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Geriatric Psychiatry and Psychotherapy
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research

Graduate School:

Graduate School for Health Sciences (GHS)

UniBE Contributor:

Vallejo, Vanessa; Cazzoli, Dario; Rampa, Luca; Zito, Giuseppe Angelo; Feuerstein, Flurin; Gruber, Nicole; Müri, René Martin; Mosimann, Urs Peter and Nef, Tobias

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

1663-4365

Publisher:

Frontiers Research Foundation

Language:

English

Submitter:

Vanessa Vallejo

Date Deposited:

21 Sep 2016 09:00

Last Modified:

21 Mar 2017 12:37

Publisher DOI:

10.3389/fnagi.2016.00200

PubMed ID:

27582704

Uncontrolled Keywords:

Alzheimer’s disease; eye movements; large hemispherical screen; search strategy; target detection; visual attention; visual exploration

BORIS DOI:

10.7892/boris.87782

URI:

https://boris.unibe.ch/id/eprint/87782

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