[Monitoring of blood parameters under course-modified MS therapy : Substance-specific relevance and current recommendations for action].

Klotz, L; Berthele, A; Brück, W; Chan, Andrew; Flachenecker, P; Gold, R; Haghikia, A; Hellwig, K; Hemmer, B; Hohlfeld, R; Korn, T; Kümpfel, T; Lang, M; Limmroth, V; Linker, R A; Meier, U; Meuth, S G; Paul, F; Salmen, Anke; Stangel, M; ... (2016). [Monitoring of blood parameters under course-modified MS therapy : Substance-specific relevance and current recommendations for action]. Der Nervenarzt, 87(6), pp. 645-659. Springer 10.1007/s00115-016-0077-1

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With the approval of various substances for the immunotherapy of multiple sclerosis (MS), treatment possibilities have improved significantly over the last few years. Indeed, the choice of individually tailored preparations and treatment monitoring for the treating doctor is becoming increasingly more complex. This is particularly applicable for monitoring for a treatment-induced compromise of the immune system. The following article by members of the German Multiple Sclerosis Skills Network (KKNMS) and the task force "Provision Structures and Therapeutics" summarizes the practical recommendations for approved immunotherapy for mild to moderate and for (highly) active courses of MS. The focus is on elucidating the substance-specific relevance of particular laboratory parameters with regard to the mechanism of action and the side effects profile. To enable appropriate action to be taken in clinical practice, any blood work changes that can be expected, in addition to any undesirable laboratory findings and their causes and relevance, should be elucidated.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Chan, Andrew and Salmen, Anke

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1433-0407

Publisher:

Springer

Language:

German

Submitter:

Stefanie Hetzenecker

Date Deposited:

19 Sep 2016 09:31

Last Modified:

23 Sep 2017 10:11

Publisher DOI:

10.1007/s00115-016-0077-1

PubMed ID:

26927677

Uncontrolled Keywords:

Blood parameters; Immunotherapy; Monitoring; Multiple Sclerosis

BORIS DOI:

10.7892/boris.87818

URI:

https://boris.unibe.ch/id/eprint/87818

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