High expression of octamer-binding transcription factor 4A, prominin-1 and aldehyde dehydrogenase strongly indicates involvement in the initiation of lung adenocarcinoma resulting in shorter disease-free intervals

Cortes-Dericks, Lourdes; Galetta, Domenico; Spaggiari, Lorenzo; Schmid, Ralph Alexander; Karoubi, Golnaz (2012). High expression of octamer-binding transcription factor 4A, prominin-1 and aldehyde dehydrogenase strongly indicates involvement in the initiation of lung adenocarcinoma resulting in shorter disease-free intervals. European journal of cardio-thoracic surgery, 41(6), e173-81. Oxford: Oxford University Press 10.1093/ejcts/ezs170

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The increasing relevance of the cancer stem cell (CSC) hypothesis and the impact of CSC-associated markers in the carcinogenesis of solid tumours may provide potential prognostic implications in lung cancer. We propose that a collective genetic analysis of established CSC-related markers will generate data to better define the role of putative CSCs in lung adenocarcinoma (LAC).

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Thoracic Surgery

UniBE Contributor:

Schmid, Ralph

ISSN:

1010-7940

Publisher:

Oxford University Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:25

Last Modified:

22 Oct 2019 22:35

Publisher DOI:

10.1093/ejcts/ezs170

PubMed ID:

22529186

Web of Science ID:

000304194800007

BORIS DOI:

10.7892/boris.8821

URI:

https://boris.unibe.ch/id/eprint/8821 (FactScience: 214454)

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