Surveillance for Hepatocellular Carcinoma in Patients with NASH

Kolly, Philippe; Dufour, Jean-François (2016). Surveillance for Hepatocellular Carcinoma in Patients with NASH. Diagnostics, 6(2), p. 22. MDPI 10.3390/diagnostics6020022

[img]
Preview
Text
Surveillance for Hepatocellular Carcinoma in Patients.pdf - Published Version
Available under License Creative Commons: Attribution (CC-BY).

Download (180kB) | Preview

European and American guidelines recommend surveillance for hepatocellular carcinoma (HCC) by performing ultrasonography on a six-month basis on an at risk population, defined by presence of cirrhosis. HCC, due to non-alcoholic steatohepatitis (NASH), is rising. Patients with NASH have a high risk of developing HCC and, therefore, have to be enrolled in a screening program. One of the challenges with NASH-induced HCC is that half of the cases arise in non-cirrhotic patients. There is a need to identify those patients in order to screen them for HCC. The obesity of these patients is another challenge, it makes ultrasound screening more difficult. Other radiological methods, such as computer tomography (CT) scans or magnetic resonance imaging (MRI), are available, but the surveillance program would no longer be cost-effective. There is a need to prospectively acquire information on cohorts of patients with NASH in order to improve the tools we have to diagnose early tumors in these patients.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR)

UniBE Contributor:

Kolly, Philippe and Dufour, Jean-François

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2075-4418

Publisher:

MDPI

Language:

English

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

28 Sep 2016 11:36

Last Modified:

09 Sep 2017 22:44

Publisher DOI:

10.3390/diagnostics6020022

PubMed ID:

27338480

Uncontrolled Keywords:

HCC; NAFLD; NASH; screening; surveillance

BORIS DOI:

10.7892/boris.88406

URI:

https://boris.unibe.ch/id/eprint/88406

Actions (login required)

Edit item Edit item
Provide Feedback