Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans

Mössner, Lone D; Schmitz, Andrea; Theurillat, Regula; Thormann, Wolfgang; Mevissen, Meike (2011). Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans. American journal of veterinary research, 72(11), pp. 1505-13. Chicago, Ill.: American Veterinary Medical Association

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To identify and characterize cytochrome P450 enzymes (CYPs) responsible for the metabolism of racemic ketamine in 3 mammalian species in vitro by use of chemical inhibitors and antibodies.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Research and Veterinary Public Health (DCR-VPH) > Veterinary Pharmacology and Toxicology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Laboratory for Clinical Pharmacology

UniBE Contributor:

Mössner, Lone, Schmitz, Andrea, Theurillat, Regula, Thormann, Wolfgang, Mevissen, Meike

ISSN:

0002-9645

Publisher:

American Veterinary Medical Association

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:25

Last Modified:

05 Dec 2022 14:07

PubMed ID:

22023129

Web of Science ID:

000296548100011

URI:

https://boris.unibe.ch/id/eprint/8908 (FactScience: 214560)

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