Methicillin-resistant Staphylococcus aureus isolated from dogs and cats in Switzerland.

Wipf, Juliette Ramona Karin; Perreten, Vincent (2016). Methicillin-resistant Staphylococcus aureus isolated from dogs and cats in Switzerland. Schweizer Archiv für Tierheilkunde, 158(6), pp. 443-450. Gesellschaft Schweizer Tierärztinnen und Tierärzte 10.17236/sat00070

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INTRODUCTION Twenty-two methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from various infected locations in domestic cats and dogs between June 2008 and September 2014 were analyzed for their genotype, genetic fingerprint, virulence and antibiotic resistance profile. Eighteen strains belonged to the clonal complex (CC) 22 [ST22(MLST)-A(PFGE)-t032(spa)-IV(SCCmec) and ST22-A-t1214-IV], 2 strains to the livestock associated MRSA ST398-t011-IV and two were individual strains of ST5-t002-II and ST1-t001-IV. They contained virulence factors such as γ-hemolysins, β-hemolysin converting phage genes, leukocidins and enterotoxins. Most widespread resistances were observed against β-lactams, trimethoprim and fluoroquinolones, but single strains also exhibited resistance to macrolides, lincosamides, aminoglycosides, tetracycline, chloramphenicol and/or mupirocin. The predominant presence of CC22 MRSA strongly indicates clonal spread of a human associated lineage in Swiss companion animals. It is therefore of public health importance to maintain a low level of MRSA infections in animals to avoid uncontrolled dissemination of MRSA clones in humans and animals.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Veterinary Public Health / Herd Health Management
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology > Molecular Bacterial Epidemiology and Infectiology
05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Wipf, Juliette Ramona Karin and Perreten, Vincent

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

0036-7281

Publisher:

Gesellschaft Schweizer Tierärztinnen und Tierärzte

Language:

English

Submitter:

Vincent Perreten

Date Deposited:

04 Oct 2016 14:12

Last Modified:

08 Feb 2017 14:22

Publisher DOI:

10.17236/sat00070

PubMed ID:

27504839

Uncontrolled Keywords:

Antibiotikaresistenz; Genotypisierung; Haustiere; Infektion; MRSA; Virulenz; antibiotic resistance; companion animals; genotyping; infection; mecA; virulence

URI:

https://boris.unibe.ch/id/eprint/89105

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