Erosion protection conferred by whole human saliva, dialysed saliva, and artificial saliva.

Baumann, Tommy; Kozik, J; Lussi, Adrian; Saads Carvalho, Thiago (2016). Erosion protection conferred by whole human saliva, dialysed saliva, and artificial saliva. Scientific Reports, 6(34760), p. 34760. Nature Publishing Group 10.1038/srep34760

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During dental erosion, tooth minerals are dissolved, leading to a softening of the surface and consequently to irreversible surface loss. Components from human saliva form a pellicle on the tooth surface, providing some protection against erosion. To assess the effect of different components and compositions of saliva on the protective potential of the pellicle against enamel erosion, we prepared four different kinds of saliva: human whole stimulated saliva (HS), artificial saliva containing only ions (AS), human saliva dialysed against artificial saliva, containing salivary proteins and ions (HS/AS), and human saliva dialysed against deionised water, containing only salivary proteins but no ions (HS/DW). Enamel specimens underwent four cycles of immersion in either HS, AS, HS/AS, HS/DW, or a humid chamber (Ctrl), followed by erosion with citric acid. During the cycling process, the surface hardness and the calcium released from the surface of the specimens were measured. The different kinds of saliva provided different levels of protection, HS/DW exhibiting significantly better protection than all the other groups (p < 0.0001). Different components of saliva, therefore, have different effects on the protective properties of the pellicle and the right proportions of these components in saliva are critical for the ability to form a protective pellicle.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > School of Dental Medicine

UniBE Contributor:

Baumann, Tommy, Lussi, Adrian, Saads Carvalho, Thiago


500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health




Nature Publishing Group




Tommy Baumann

Date Deposited:

27 Oct 2016 10:59

Last Modified:

05 Dec 2022 14:59

Publisher DOI:


PubMed ID:





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