Reliability and validity of a new dexterity questionnaire (DextQ-24) in parkinson's disease

Vanbellingen, Tim; Nyffeler, Thomas; Nef, Tobias; Kwakkel, G; Bohlhalter, Stephan; van Wegen, EE (2016). Reliability and validity of a new dexterity questionnaire (DextQ-24) in parkinson's disease. Parkinsonism & related disorders, 33, pp. 78-83. Elsevier 10.1016/j.parkreldis.2016.09.015

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Patients with Parkinson's disease exhibit disturbed dexterity. Validated self-reported outcomes for dexterity in Parkinson's disease are lacking. The aim of this study was to investigate the reliability, content and construct validity of a new Dexterity Questionnaire 24.
One hundred and three patients with Parkinson's disease completed the Dexterity Questionnaire 24 (score range 24-96), at baseline and four weeks later. The internal consistency was determined. Test-retest reliability was assessed in a subgroup (N = 44). Standard error of measurements and the minimal detectable change were defined. The construct validity was examined in the whole group (N = 103). Floor and ceiling effects were investigated.
The internal consistency of the Dexterity Questionnaire 24 was high (α = 0.91). High test-retest reliability was found (Intra Class Correlation Coefficient = 0.91, Confidence interval: 0.84-0.95). Standard error of measurement was 2.9 and minimal detectable change was 8 points. (i.e., 11%). Good structural, convergent and divergent validity of the Dexterity questionnaire 24 was found (r = 0.73 with Activities of Daily Living-subscale of the Parkinson's Disease Questionnaire-39, and r = 0.66, and r = 0.50, p-values all < 0.0001, respectively with the subscales II and III of the Movement Disorders Society-Unified Parkinson Disease Rating Scale). Low not significant correlations were found between the Dexterity Questionnaire 24 and the subscales stigma and social support (r = 0.20, and r = 0.14 respectively). No floor or ceiling effects were found for the total Dexterity Questionnaire 24.
The Dexterity Questionnaire 24 is valid and reliable for evaluating dexterity in patients with Parkinson's disease.

Item Type:

Journal Article (Original Article)


10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
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04 Faculty of Medicine > University Psychiatric Services > University Hospital of Geriatric Psychiatry and Psychotherapy
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research
04 Faculty of Medicine > University Psychiatric Services

UniBE Contributor:

Vanbellingen, Tim; Nyffeler, Thomas; Nef, Tobias and Bohlhalter, Stephan


600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology








Vanessa Vallejo

Date Deposited:

08 Dec 2016 13:51

Last Modified:

05 Dec 2022 15:00

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

Dexterity, Parkinson's disease, Patient reported questionnaire, Reliability, Validity




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