Minimally Invasive Extracorporeal Circulation Circuit Is Not Inferior to Off-Pump Coronary Artery Bypass Grafting: Meta-Analysis Using the Bayesian Method.

Winkler, Bernhard; Heinisch, Paul P; Gahl, Brigitta; Aghlmandi, Soheila; Jenni, Hans Jörg; Carrel, Thierry P (2017). Minimally Invasive Extracorporeal Circulation Circuit Is Not Inferior to Off-Pump Coronary Artery Bypass Grafting: Meta-Analysis Using the Bayesian Method. Annals of thoracic surgery, 103(1), pp. 342-50. Elsevier 10.1016/j.athoracsur.2016.08.067

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The pathophysiologic side effects of cardiopulmonary bypass have already been identified. Minimally invasive extracorporeal circulation technologies (MiECT) and off-pump coronary artery bypass graft surgery (OPCABG) aim to reduce these problems. This metaanalysis provides a comparison of MiECT and OPCABG in randomized and observational studies. A fully probabilistic, Bayesian approach of primary and secondary endpoints was conducted. MiECT does not give inferior results when compared with OPCABG. However, there is a trend to borderline significantly higher blood loss in this group in randomized controlled trials. The question whether MiECT is equivalent to OPCABG can be answered with the affirmative, but long-term follow-up data are needed to detect any advantage over time.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine

Graduate School:

Graduate School for Health Sciences (GHS)

UniBE Contributor:

Winkler, Bernhard; Heinisch, Paul Philipp; Gahl, Brigitta; Aghlmandi, Soheila; Jenni, Hansjoerg and Carrel, Thierry

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

0003-4975

Publisher:

Elsevier

Language:

English

Submitter:

Daniela Huber

Date Deposited:

07 Dec 2016 10:07

Last Modified:

05 Jan 2017 09:49

Publisher DOI:

10.1016/j.athoracsur.2016.08.067

PubMed ID:

27780561

BORIS DOI:

10.7892/boris.90557

URI:

https://boris.unibe.ch/id/eprint/90557

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