Sleep & Metabolism: the multitasking ability of lateral hypothalamic inhibitory circuitries.

Gutierrez Herrera, Carolina; Ponomarenko, Alexey; Korotkova, Tatiana; Burdakov, Denis; Adamantidis, Antoine Roger (2017). Sleep & Metabolism: the multitasking ability of lateral hypothalamic inhibitory circuitries. Frontiers in neuroendocrinology, 44, pp. 27-34. Elsevier 10.1016/j.yfrne.2016.11.002

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The anatomical and functional mapping of lateral hypothalamic circuits has been limited by the numerous cell types and complex, yet unclear, connectivity. Recent advances in functional dissection of input-output neurons in the lateral hypothalamus have identified subset of inhibitory cells as crucial modulators of both sleep-wake states and metabolism. Here, we summarize these recent studies and discuss the multi-tasking functions of hypothalamic circuitries in integrating sleep and metabolism in the mammalian brain.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Gutierrez Herrera, Carolina and Adamantidis, Antoine Roger

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1095-6808

Publisher:

Elsevier

Language:

English

Submitter:

Stefanie Hetzenecker

Date Deposited:

13 Jan 2017 17:23

Last Modified:

13 Jan 2017 17:23

Publisher DOI:

10.1016/j.yfrne.2016.11.002

PubMed ID:

27884682

Uncontrolled Keywords:

Food intake; GABA; Histamine; Hypocretin; Melanin concentrating hormone; Metabolism; Orexin; Sleep

BORIS DOI:

10.7892/boris.90721

URI:

https://boris.unibe.ch/id/eprint/90721

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