A dominant lineage of Mycoplasma bovis is associated with an increased number of severe mastitis cases in cattle

Bürki, Sibylle; Spergser, Joachim; Bodmer, Michèle; Pilo, Paola (2016). A dominant lineage of Mycoplasma bovis is associated with an increased number of severe mastitis cases in cattle. Veterinary microbiology, 196, pp. 63-66. Elsevier 10.1016/j.vetmic.2016.10.016

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Mycoplasma bovis is the most frequent etiologic agent of bovine mycoplasmosis. It causes various diseases in bovines and considerable economic loss due to the lack of effective treatment or preventive measures such as vaccination. In contrast to the US, where M. bovis-mastitis has been reported for a long time, M. bovis infections in Switzerland and Austria were predominantly associated with pneumonia and subclinical mastitis. However, since 2007 the situation has changed with the emergence of severe M. bovis-associated mastitis cases in both countries. In order to evaluate the molecular epidemiology of the bacteria isolated from these infections, recent and old Swiss, along with recent Austrian M. bovis isolates were analyzed by a typing method displaying intermediate resolution of evolutionary relationships among isolates called Multi-Locus Sequence Typing (MLST). The analysis of Swiss and Austrian M. bovis isolates revealed two major lineages. Isolates collected since 2007 in both countries cluster in the lineage I including ST5, ST33, ST34, 36, and ST38-40 (clonal complex 1), while all Swiss isolates recovered before 2007 cluster in the lineage II comprising ST17 and ST35 (clonal complex 5). Further investigations are necessary to understand if lineage I has a higher predilection or virulence toward mammary gland cells than the old lineage or if other factors are involved in the increased number of severe mastitis cases.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Veterinary Public Health / Herd Health Management
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Bürki, Sibylle; Bodmer, Michèle and Pilo, Paola

Subjects:

600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

0378-1135

Publisher:

Elsevier

Language:

English

Submitter:

Daniela Fasel

Date Deposited:

16 Feb 2017 10:10

Last Modified:

09 Nov 2018 08:16

Publisher DOI:

10.1016/j.vetmic.2016.10.016

PubMed ID:

27939157

Uncontrolled Keywords:

Bovine; MLST; Mastitis; Mycoplasma bovis

BORIS DOI:

10.7892/boris.92198

URI:

https://boris.unibe.ch/id/eprint/92198

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