Role of fluorine-18 fluorodeoxyglucose PET/CT in head and neck oncology: the point of view of the radiation oncologist.

Cacicedo, Jon; Navarro, Arturo; Del Hoyo, Olga; Gomez-Iturriaga, Alfonso; Alongi, Filippo; Medina, Jose A; Eliçin, Olgun; Skanjeti, Andrea; Giammarile, Francesco; Bilbao, Pedro; Casquero, Francisco; de Bari, Berardino; Dal Pra, Alan (2016). Role of fluorine-18 fluorodeoxyglucose PET/CT in head and neck oncology: the point of view of the radiation oncologist. British journal of radiology, 89(1067), p. 20160217. British Institute of Radiology 10.1259/bjr.20160217

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Squamous cell carcinoma is the most common malignant tumour of the head and neck. The initial TNM staging, the evaluation of the tumour response during treatment, and the long-term surveillance are crucial moments in the approach to head and neck squamous cell carcinoma (HNSCC). Thus, at each of these moments, the choice of the best diagnostic tool providing the more precise and larger information is crucial. Positron emission tomography with fluorine-18 fludeoxyglucose integrated with CT ((18)F-FDG-PET/CT) rapidly gained clinical acceptance, and it has become an important imaging tool in routine clinical oncology. However, controversial data are currently available, for example, on the role of (18)F-FDG-PET/CT imaging during radiotherapy planning, the prognostic value or its real clinical impact on treatment decisions. In this article, the role of (18)F-FDG-PET/CT imaging in HNSCC during pre-treatment staging, radiotherapy planning, treatment response assessment, prognosis and follow-up is reviewed focusing on current evidence and controversial issues. A proposal on how to integrate (18)F-FDG-PET/CT in daily clinical practice is also described.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Eliçin, Olgun and Dal Pra, Alan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0007-1285

Publisher:

British Institute of Radiology

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

16 Mar 2017 09:22

Last Modified:

01 Mar 2018 15:24

Publisher DOI:

10.1259/bjr.20160217

PubMed ID:

27416996

BORIS DOI:

10.7892/boris.92694

URI:

https://boris.unibe.ch/id/eprint/92694

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