A mathematical approach to human pterygium shape.

Pajic, Bojan; Vastardis, Iraklis; Rajkovic, Predrag; Pajic-Eggspuehler, Brigitte; Aebersold, Daniel; Cvejic, Zeljka (2016). A mathematical approach to human pterygium shape. Clinical ophthalmology, 10, pp. 1343-1349. Dove Medical Press 10.2147/OPTH.S106611

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PURPOSE Pterygium is a common lesion affecting the population in countries with high levels of ultraviolet exposure. The final shape of a pterygium is the result of a growth pattern, which remains poorly understood. This manuscript provides a mathematical analysis as a tool to determine the shape of human pterygia. MATERIALS AND METHODS Eighteen patients, all affected by nasal unilateral pterygia, were randomly selected from our patient database independently of sex, origin, or race. We included all primary or recurrent pterygia with signs of proliferation, dry eye, and induction of astigmatism. Pseudopterygia were excluded from this study. Pterygia were outlined and analyzed mathematically using a Cartesian coordinate system with two axes (X, Y) and five accurate landmarks of the pterygium. RESULTS In 13 patients (72%), the shape of the pterygia was hyperbolic and in five patients (28%), the shape was rather elliptical. CONCLUSION This analysis gives a highly accurate mathematical description of the shape of human pterygia. This might help to better assess the clinical results and outcome of the great variety of therapeutic approaches concerning these lesions.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Pajic, Bojan and Aebersold, Daniel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1177-5467

Publisher:

Dove Medical Press

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

16 Mar 2017 11:16

Last Modified:

19 Sep 2017 06:58

Publisher DOI:

10.2147/OPTH.S106611

PubMed ID:

27555741

Uncontrolled Keywords:

etiology; limbal stem cells; mathematical shape analysis; pterygium; stem cells dysfunction

BORIS DOI:

10.7892/boris.92750

URI:

https://boris.unibe.ch/id/eprint/92750

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